Name/Model #
quantitative ultrasound (QUS), forward and backward scattered second harmonic generation (SHG), enhance backscatter, optical coherence tomography (OCT)
271 Animal Sciences, 1675 Observatory Drive, Madison, WI, 53706


LINK is an instrumentation collaboration between the Medical Engineering group in the Morgridge Institute for Research and LOCI investigators that combines quantitative ultrasound (QUS), forwards and backwards scattered second harmonic generation microscopy (SHG), and two optical scattering techniques, enhance backscatter and optical coherence tomography (EBS and OCT, respectively) to analyze collagen organization in intact animal and human tissues. Paul Campagnola, Kevin Eliceiri, Tim Hall and Jeremy Rogers are collaborating under National Science Foundation Major Research Instrumentation funding and the Morgridge Multiscale Initative on how imaging techniques of different spatial scales can elucidate the role of collagen organization in cancer. 

"Collagen imaging: Bridging the gap between microscopy and the clinic"

National Science Foundation Major Research Instrumentation Program