For the best performance, a fast CPU is needed—at least 1 GHz for Macintosh, or 2 GHz for Windows and Linux machines. VisBio can run on slower machines, but some features may seem sluggish, particularly animation. Since VisBio is written in Java, and Java is rather slow on the Mac, we recommend a strong system if you are running Mac OS X—a G5 will perform much better than an older G4.

We strongly recommend at least 512 MB of system RAM, and suggest 1 GB or more for memory intensive features such as volume rendering of large datasets. Lastly, for a responsive 3D display, a good video card is recommended. Any recent card should provide enough performance for VisBio's needs.