Sept. 17 - Michael Pinkert
Monday, September 17, 2018, 4:00pm-5:00pm
Michael Pinkert (student of Drs. Walter Block and Kevin Eliceiri), Research Assistant, Dept of Medical Physics, UW-School of Medicine & Public Health
Title: Tools for multiscale imaging of collagen in cancer
The organization of collagen fibers plays an important role in many types of cancer, from microscale fiber structure affecting cellular processes such as metastasis, to macroscale density in organs being a component of cancer risk. However, there is a lack of accessible tools that can study collagen across multiple spatial scales, making it difficult to fully understand the effects of collagen organization on cancer. This talk introduces hardware and software tools to perform multiscale imaging of collagen. This includes a platform that combines ultrasound and second-harmonic-generation microscopy, alongside software that can register and analyze collagen across large volumes.