Hometown: Shaoyang, Hunan Province, China
Yuming Liu is a Senior Scientist at the University of Wisconsin–Madison’s Laboratory for Optical and Computational Instrumentation (LOCI) directed by Professor Kevin Eliceiri. He earned his PhD in Systems Engineering from Zhejiang University and completed postdoctoral training in optical imaging at Oregon Health and Science University before joining LOCI in 2012.
Dr. Liu’s research focuses on data-driven computational microscopy to quantify the role of the collagen-rich tumor microenvironment (TME) in cancer invasion and progression. He is a key researcher in LOCI’s efforts to develop “smart” microscopy systems—incorporating multiphoton, second harmonic generation, advanced polarized light, fluorescence lifetime, and hyperdimensional imaging—to study the interactions between collagen fibers and tumor/immune cells. These systems integrate automated open-source hardware control (Micro-Manager/OpenScan) with real-time analysis including deep learning-based methods for image segmentation, denoising, and resolution enhancement. Dr. Liu is the lead developer of a widely utilized open-source TME analysis platform, CT-FIRE/CurveAlign. He is currently expanding the platform’s features in Python to create comprehensive, automated pipelines and provide integration with the next generation of smart microscopes.